Scientists grow early human egg cells from blood cells in first
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Scientists have for the first time grown early-stage human egg cells from blood cells, according to a study published July 20. The breakthrough could offer new options for fertility treatment. However, the eggs are not yet mature and require further development.
The Breakthrough
Researchers at a Japanese university reprogrammed blood cells into induced pluripotent stem cells, then guided them to form early oogonia, the precursors to egg cells. The study, published in Nature, marks the first time human oogonia have been created from somatic cells. The team used a chemical cocktail to mimic natural development.
Fertility Implications
The technique could eventually help women with premature ovarian failure or genetic disorders to produce their own eggs. Currently, the oogonia cannot develop into mature eggs outside the body. The researchers aim to achieve full maturation in the lab within five years.
Embryo Model from Stem Cells
Researchers at the Weizmann Institute created a model of a 14-day-old human embryo using stem cells, without sperm, eggs, or a womb. The model released hormones that turned a pregnancy test positive, mimicking natural embryo development.
Separate Embryo Model Research
A separate study at Israel's Weizmann Institute created a model resembling an early human embryo using stem cells without sperm, egg, or womb. The model released hormones that turned a pregnancy test positive.
What's Next
The team plans to refine the process to produce mature eggs within five years. It remains unclear whether the eggs will be viable for fertilization or carry genetic abnormalities.
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Scientists grow early human egg cells from blood cells in first
